Hopeful Bible Verses for Depression and Anxiety

8 min read

Depression and anxiety can sit like clouds on us. Dulling and dampening everything. These helpful Bible verses for depression and anxiety have the power and potential to cut through the grey in a moment. 

Our thought lives can be real battlefields but God’s living word can bring light, hope and freedom.

Whether you’re fighting a personal battle with depression, or someone you love is, use these Bible verses to bring fresh encouragement.  

What Bible verses can I use to help me cope with depression?

Are you ready for some really good news? Not only can Bible verses for depression help you cope they can also show you the path to freedom. 

Dealing with depression is a challenging and often isolating experience. Reading through scripture can really help as it reveals just how known and loved you are. 

There are Bible verses for depression that are like balm for the soul. They remind you that God is for you and that He is wildly, crazily, irrevocably in love with you. He is the most doting dad there ever was! 

Let these Bible verses wash over you, reminding you of God’s eternal love for you. 

Psalm 34:18 

The LORD is close to the brokenhearted and saves those who are crushed in spirit.”

This verse is a reminder that God is always with you, even when it feels like no one else is. When you’re feeling depressed and alone, it can be easy to feel like no one cares. But this verse reassures you that God is close to you, holding you up and saving you from your pain.

Philippians 4:8 

“..whatever is true, whatever is noble, whatever is right, whatever is pure, whatever is lovely, whatever is admirable…think about such things.”

This verse encourages you to focus on positive, uplifting thoughts. When you’re feeling depressed, it can be easy to get caught up in negative thinking patterns. But this verse reminds you to focus on the good things in your life, and to look for the beauty and goodness in the world around you.

Isaiah 41:10

“So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”

This verse is another reminder that God is always with you, ready to strengthen and support you during times of struggle. When you’re feeling overwhelmed by depression, this verse can provide comfort and reassurance that you’re not alone, and that you have the God of the universe on your side.

Romans 8:38-39

“For I am convinced…neither the present nor the future, nor any powers…nor anything else in all creation, will be able to separate us from the love of God that is in Christ Jesus our Lord.”

This powerful verse emphasizes the never-ending love and support of God, which can provide a tangible sense of peace and security during difficult times. When you’re feeling depressed, it can be easy to feel disconnected from God or from others around you. But this verse reminds you that nothing can separate you from God’s love, and that you are never truly alone.

Psalm 42:5 

“Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”

This verse acknowledges the reality of depression, but also encourages you to put your hope in God. It can be easy to feel overwhelmed by the weight of your emotions, but this verse reminds you that there is always hope. By turning to God and putting your trust in Him, you can find the strength to overcome your struggles and praise Him for His faithfulness.

Philippians 4:6-7 

“Do not be anxious about anything, but in every situation…present your requests to God. And the peace of God..will guard your hearts and your minds in Christ Jesus.”

This verse encourages you to turn to God in prayer and to trust Him with your worries and anxieties. By doing so, you can experience the peace that comes from knowing that God is in control. This peace may not make sense to the world around you, but it will guard your heart and mind against the overwhelming effects of depression.

Psalm 55:22 

“Cast your cares on the Lord and he will sustain you; he will never let the righteous be shaken.”

This verse reminds us to give our worries and burdens over to God, trusting that He will take care of us. When you’re struggling with depression, it can be difficult to let go of the weight you’re carrying. But this verse encourages you to trust in God’s strength and promise of sustenance. By casting your cares on Him, you can find relief and stability in the midst of your struggles.

Depression can be a difficult and isolating experience, but it doesn’t have to be one you face alone. By turning to God and His word, you can find the strength, hope, and comfort you need to overcome your struggles. Take heart and know that you are never truly alone. 

God is with you, and His love and care for you will never falter.

Are there any bible verses that discuss overcoming depression?

Once you start to really get to grips with the Bible, you realise there’s usually a verse or two for nearly every challenge we face in life. Part of the beauty of Jesus coming as man was that He experienced the highs and lows of life too. 

The verses above are great to use in your quiet time. Mediate on them and use them as mental lifelines to hold onto in hard times. 

There are also powerful stories in the Bible of heroes of the faith who thrived, against the odds, thanks to God’s support and power. 

Read through the stories of these Biblical characters and let how their stories overcame the odds inspire your own. 


Daniel and his friends were taken captive and forced to work for an oppressive ruler. In a truly dangerous situation Daniel stayed connected to God, praying three times a day as he usually would. This defiant act nearly cost him his life but God showed up in a big, powerful way, saving him from hungry lions. This story is a brilliant reminder of how if we stay connected to God and prioritize our intimacy with Him, we can see Him move as our savior and redeemer. 


Esther was taken to live in the King’s court as a young woman. Away from her uncle, who had raised her, and everything she knew, she found herself alone and vulnerable in a hostile situation. Her faithfulness and trust in God’s word meant she ended up saving God’s people by bravely petitioning the King. It’s a beautiful story and one that underlines how, no matter how difficult your surroundings, God can bring breakthrough and redemption to your situation. 


Job gets caught up in a supernatural discussion with the accuser claiming that not one of God’s people is truly good and truly loves Him. As a result he endures the absolute worst of tragedies including loosing his family, his possessions and his health. And yet, while he questions everything and experiences the full spectrum of emotions, his belief in a good and sovereign God remains. His story is a truly inspiring one to cling onto when it feels like out world is falling apart. 

What Bible verses can I turn to for comfort when dealing with depression?

Along with famous Bible verses for depression like Isaiah 41: 10 which says “Do not fear, for I am with you” or John 16: 33 where Jesus says: “In me you may have peace” there’s another way to find comfort through scripture.

Holding onto specific verses and using them to anchor you in difficult times is a brilliant way to use Bible verse for depression. 

But, you can also focus on getting a broad understanding of the overall picture that the Bible is painting. 

Too often we overlook the Old Testament. When we do that we miss out on so much fo the beauty, power and promise of the New Testament. 

When you read through the Bible, noticing its themes and how it repeats itself – even thousands of years apart – you begin to understand the overarching story that God is telling. 

In short? God is orchestrating history in order to be reconciled with His children. His ultimate desire is to live in complete oneness and peace with us. 

And finally? Every day we are closer to the day when this world will be made new. When beauty, joy and peace will reign, and tears, pain and death will be no more. 

Oh and don’t forget, we’re invited to live with a foretaste of that heavenly goodness, today, through the abiding of the Holy Spirit in us. 

Studying the picture the Bible paints helps you realise that nothing we face today is new. No challenge, evil or threat. God’s people have endured through the hardest of times and have seen His provision and mercy. And we are no different. 

Does the Bible have any verses that talk about hope in the face of depression?

Psalm 40: 1-3 is a brilliant Bible verse to hone in when you’re looking for hope. 

“I waited patiently for the Lord; he turned to me and heard my cry. He lifted me out of the slimy pit, out of the mud and mire; he set my feet on a rock and gave me a firm place to stand.”

Let this verse encourage you to wait on God during seasons of depression, anxiety and other real challenges in life. God is with us in the very depths of our suffering and He promises us a firm place to stand. Trust in God to be with you and to turn your pain into hope and a promise of a future. 

Download Glorify app

Try Glorify for free today!

Download now!